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. 2012 Apr 18;287(24):20270–20280. doi: 10.1074/jbc.M112.369561

TABLE 3.

Binding affinity of empedopeptin to phospholipid model membranes

Association rate (ka), dissociation rate (kd), and overall binding affinity (kD) of empedopeptin as determined by the quartz crystal microbalance technique either in the absence or presence of 1.25 mm CaCl2.

ka kd kD
m−1s−1 s−1 μm
Without Ca2+ 2835 ± 507 2.10 × 10−3 ± 0.86 × 10−3 0.77 ± 0.41
1.25 mm Ca2+ 4736 ± 1262 1.47 × 10−3 ± 0.70 × 10−3 0.30 ± 0.11