TABLE 3.
Binding affinity of empedopeptin to phospholipid model membranes
Association rate (ka), dissociation rate (kd), and overall binding affinity (kD) of empedopeptin as determined by the quartz crystal microbalance technique either in the absence or presence of 1.25 mm CaCl2.
ka | kd | kD | |
---|---|---|---|
m−1s−1 | s−1 | μm | |
Without Ca2+ | 2835 ± 507 | 2.10 × 10−3 ± 0.86 × 10−3 | 0.77 ± 0.41 |
1.25 mm Ca2+ | 4736 ± 1262 | 1.47 × 10−3 ± 0.70 × 10−3 | 0.30 ± 0.11 |