FIGURE 1.

Mice with a homozygous “funky” mutation have transient hair loss (A) and a failure to thrive (B). A, funky mice present with baldness behind the neck around P17, which progresses down the trunk (P21) toward the tail (P24) after which the hair grows back in the same order. B, growth curves comparing homozygous funky males and females to normal littermates. Homozygous mice show a reduction in growth rate from the age of 15 days. n = 6 for affected males (M, Affected); n = 33 for control males (M, Control); n = 10 for affected females (F, Affected); n = 20 for control females (F, Control); p = 10⁻⁵ for males; p = 10⁻⁵ for females. Error bars, S.E.