Fig. 2.

Twenty nine regulatory elements related to bone formation were identified and localized in the 3788-Ambn-lacZ construct. Abbreviations: RFX1, MHC class II regulatory factor RFX1; Pax-5, paired box protein; MEF-2, myocyte-specific enhancer factor 2; MAF, V-maf musculoaponeuretic fibrosarcoma oncogene homolog (avian); Octamer, NONO, non POU-domain-containing octamer binding protein; Oct-1, Pou2f1 POU-domain class 2; CDP, CCAT displacement protein (= Cux1); ISGF-3, signal transducer and activator of transcription 1-alpha/beta (transcription factor ISGF-3 components p91/p84) = STAT-1; CdxA, Cdx1/CDX1 (a caudal-type homeobox intestine-specific transcription factor); E47, E12/E47 basic helix–loop–helix transcription factor (the E2A gene product); PLZF, promylocytic leukemia zinc finger; YY1, Yin and Yang 1 (synonym NMP1); PPARγ:RXRα, peroxisome proliferator-activated receptor gamma; retinoic acid receptor alpha; Kid-3, kidney, ischemia, and developmentally regulated protein 3 (= Zinc finger protein 354c and AJ18); BCL6, B-cell lymphoma 6 protein homolog; TEL2, telomere length regulation protein TEL2 homolog; Cart-1, cartilage homeoprotein 1 (= ALX 1); LEF1/TCF1, lymphoid enhancer-binding factor 1/T-cell-specific transcription factor 1; LEF1, lymphoid enhancer-binding factor 1; C/EBPα, CCAAT enhancer binding protein alpha/gamma homolog; AP-1, transcription factor AP-1 (also known as activator protein 1 and proto-oncogene c-jun, gene name: Jun); MYB, V-maf musculoaponeurotic fibrosarcoma oncogene homolog; GATA-X, GATA binding factor, erythroid transcription factor; PEBP, polyoma enhancer binding protein 2; PEBP/OSE2, Cbfa1/Runx2 binding motif; SOX, transcription factor Sox (SRY-related HMG box); Msx, homeobox protein MSX (Msh homeobox-like protein) (Hox-7) (Hox-7.1); GATA-1, GATA binding factor 1, erythroid transcription factor; Gli1, glioma-associated oncogene homolog.