Figure 2. Renal mRNA expression of efflux transporters in vehicle- and STZ-treated mice during pregnancy.
Total RNA was isolated from kidneys and mRNA levels were quantified using real-time quantitative PCR. The mRNA data for (A) apical transporters and (B) basolateral transporters are presented as means normalized to Rpl13a ± SE (n= 3-8 animals). Asterisks (*) represent a statistical difference compared to vehicle non-pregnant mice (p ≤ 0.05); Daggers (†) represent a statistical difference between vehicle and STZ-treated pregnant mice (p ≤ 0.05); Double daggers (‡) represent a statistical difference between STZ-treated non-pregnant and pregnant mice (p ≤ 0.05).