Fig 2.

Adaptive transfer of Gr1⁺CD11b⁺ cells recovered from early septic mice exaggerate, whereas those from late septic mice attenuate, the early systemic inflammatory response of sepsis. Sepsis was induced by CLP. Bone marrow cells were harvested at day3 (D3) and day 12 (D12) after CLP from a separate group of mice. Gr1⁺ CD11b⁺ cells were purified by magnetic cell sorting and injected (4 × 10⁶ cells) i.v. into mice that had just undergone CLP. Control mice received 100 μl saline. Survival was recorded for 21 days. There were no significant differences in survival after day 7.