Table 1. Hemodynamic parameters in the isolated postcapillary venules of WT and eNOS-/- mice.
| Venule diameter, μm | Centerline velocity, mm/s | Calculated wall shear rate, per s | |
|---|---|---|---|
| WT | 30.1 ± 2.6 | 2.2 ± 0.2 | 396.1 ± 50.8 |
| WT + ODQ | 33.7 ± 2.6 | 2.9 ± 0.4 | 428.2 ± 52.5 |
| eNOS-/- | 30.1 ± 2.1 | 2.4 ± 0.2 | 423.0 ± 53.1 |
| eNOS-/- + BAY (0.3 μM) | 29.7 ± 1.9 | 2.4 ± 0.2 | 374.0 ± 38.5 |
| eNOS-/- + BAY (1 μM) | 33.7 ± 1.9 | 2.5 ± 0.3 | 393.9 ± 44.5 |
| eNOS-/- + BAY + ODQ | 33.9 ± 2.2 | 2.4 ± 0.4 | 343.5 ± 35.0 |
| eNOS-/- + DEA-NO (1 μM) | 32.7 ± 2.5 | 2.5 ± 0.3 | 401.1 ± 37.8 |
| IL-1β (90 min) | 29.5 ± 3.7 | 1.9 ± 0.2 | 403.6 ± 23.1 |
| IL-1β (90 min) + BAY (1 μM) | 27.2 ± 1.2 | 1.9 ± 0.1 | 363.4 ± 22.5 |
| IL-1β (180 min) | 25.7 ± 2.1 | 1.9 ± 0.2 | 381.9 ± 31.2 |
| IL-1β (180 min) + BAY (1 μM) | 25.0 ± 2.0 | 1.9 ± 0.2 | 382.0 ± 27.4 |
n ≥ 7; P > 0.05 for all compared to WT control.