Table 1.

Strains and plasmids used in this study

Strain or plasmid	Relevant characteristic	Source or reference
M. tuberculosis strain 1424	M. tuberculosis wild-type H37Rv derivative, streptomycin resistant	13
ΔuvrA	uvrA deletion mutant	40
ΔuvrD1	uvrD1 deletion mutant	This study
ΔuvrA uvrD	uvrA uvrD1 double deletion mutant	This study
pUvrD1::gm-rpsL	Targeting plasmid for removal of base pairs 299-1633 of uvrD1 ORF	This study
Z205	uvrD1 complementing vector, uvrD1 in pMV361 used for in vitro experiments	This study
pAW33	uvrD1 complementing vector, uvrD1 in pKP201 used for in vivo experiments	This study
uvrD1comp	ΔuvrD1 plus either Z205 or pAW33	This study