ETIOLOGY |
NOMID is an autoinflammatory disorder characterized by the triad of neonatal onset of cutaneous symptoms, arthropathy and central nervous system symptoms. |
INCIDENCE |
Since NOMID is a newly discovered condition and is a very rare condition, the actual incidence and prevalence of the disease is difficult to determine. |
GENDER RATIO |
Males and females are affected equally |
AGE PREDILECTION |
Most children are affected before age of 10 years old |
RISK FACTORS |
It is discovered to be due to alterations in a gene identified as the Cold-induced Auto-inflammatory Syndrome 1 (CIAS1) gene (Autosomal Dominant). |
TREATMENT |
The treatment is supportive, or aimed solely at controlling symptoms and maximizing function. Some reports showed that early treatment with anakinra related with better outcome of arthropathy. |
PROGNOSIS |
The prognosis for patients with NOMID is not good and debilitating especially due to the arthropathy. |
FINDINGS ON IMAGING |
Bulky mass in the physis with heterogenous calcification within. |