Table 1.
Etiology: | Spindle cell proliferation often associated with post-surgical trauma |
Incidence: | 0.2% of breast neoplasms |
Age predilection: | Mean age 37, range 13–80 years |
Risk factors: | Trauma, post-surgical trauma, exogenous hormone treatments, association with familial adenomatous polyposis |
Treatment: | Wide local excision is standard Radiation therapy in selected cases Hormonal therapy in selected cases Chemotherapy in selected cases |
Prognosis: | No metastatic potential Local recurrence rate 21–27% usually within 3 years Response to medical treatment variable Spontaneous regression rare |