Table 6.
Frequency of the mutations in katG 315 and/or the inhA promoter region −15 in INHr isolates in India and China reported by five groups
Locus | % Mutations in different geographic regionsa |
|||||
---|---|---|---|---|---|---|
Northern India (n = 121) | Southern India (n = 70) | Southern China (n = 50) | Eastern China 1 (n = 131) | Eastern China 2c (n = 242) | This study (n = 113) | |
katG 315 | 55.4 | 64.3 | 60.0 | 61.8 | 72.7 | 82.3 |
inhA −15 | 25.6 | 11.4 | 8.0 | 21.4 | 8.3 | 10.6 |
Othersb | 27.3 | 28.6 | 36.0 | 18.3 | 21.5 | 10.8 |
Values include isolates with mutations at both loci. Source references for the various regions were as follows: northern India (16), southern India (22), southern China (4), eastern China 1 (10), and eastern China 2 (12).
Includes both other mutations and no mutations.
Collected only in Shanghai (n = 242).