Fig 2.
Schematic representation of the orfX-ACME-SCCmec structure from M08/0126 ST22-MRSA-IV (GenBank accession number FR753166) (A), Sa0059 ST239-MRSA-III (clade 1 isolate; GenBank accession number JQ412578) (B), and JKD6008 ST239-MRSA-III (GenBank accession number CP002120) (C). Only the following selected genes are annotated: the arginine deiminase pathway (arcCBDAR), the SCCmec III cassette recombinases (ccrB3, ccrA3), and the determinants encoding resistance to bleomycin (ble), aminoglycosides (aadD), methicillin (mecA), and cadmium (cadDAX). Arrowheads within gray rectangles denote the transposase (and the direction of its transcription) of IS257 (also referred to as IS431). DR, direct repeat. Black rectangles denote orfX.
