Table 3.

Drug accumulation in final model

Compound	Accumulation (95% CI) from day 0 to day:
	3	7	12
ZDV-TP	31% increase (14%, 51%); P = 0.0002	37% increase (14%, 64%); P = 0.0009	29% increase (12%, 48%); P = 0.0004
3TC-TP	177% increase (139%, 220%); P < 0.0001	231% increase (179%, 291%); P < 0.0001	245% increase (199%, 297%); P < 0.0001
ZDV plasma	4% increase (−9%, 19%); P = 0.57	17% decrease (−27%, −5%); P = 0.0077	18% decrease (−29%, −5%); P = 0.0057
3TC plasma	26% increase (17%, 36%); P < 0.0001	22% increase (12%, 32%); P < 0.0001	20% increase (12%, 30%); P < 0.0001