Table 1.
Baseline characteristics of study participants
| Parameter | Duo-cotecxin values (29) (historical) (n = 22)a | Artequick values (present study) (n = 12)a | P value |
|---|---|---|---|
| Age (yr) | 6.9 ± 1.4 | 7.1 ± 1.5 | 0.790b |
| Sex (% male) | 17 (86) | 8 (66) | 0.687c |
| Weight (kg) | 19.1 ± 3.8 | 18.3 ± 3.1 | 0.986b |
| Axillary temp (°C) | 37.2 ± 1.2 | 36.3 ± 0.7 | 0.034b |
| No. (%) with P. falciparum parasitemia | 19 (86) | 11 (92) | 1.00c |
| Parasite density (per μl of whole blood) | 13,360 [6,900–51,650] | 26,270 [3,480–35,30] | 0.736b |
| No. (%) with P. vivax parasitemia | 2 (9.1) | 1 (8) | 1.00c |
| No. (%) with P. malariae parasitemia | 1 (4.5) | 0 (0) | 1.00c |
| Hemoglobin (g/dl) | 8.6 ± 1.8 | 9.3 ± 2.1 | 0.168b |
| Total PQ base dose (mg/kg) | 35.3 ± 4.4 | 38.3 ± 5.8 | 0.136b |
| Total DHA dose (mg/kg) | 7.7 ± 1.0 | ||
| Total ART dose (mg/kg) | 6.4 ± 1.0 |
a
Data represent number (%), mean ± SD, or median [interquartile range {IQR}], as indicated.
b
Mann-Whitney U test.
c
Fisher's exact test.