Table 1.
Characteristics of the study isolatesa
| Isolate | PVL | MLST type | PFGE type | OXA MIC (μg/ml) | VAN MIC (μg/ml) | Δlog10 CFU reduction at: |
|||
|---|---|---|---|---|---|---|---|---|---|
| 6 h in dicloxacillin time-kill assays | 24 h in dicloxacillin time-kill assays | 6 h in vancomycin time-kill assays | 24 h in vancomycin time-kill assays | ||||||
| 446 | + | 80 | Ia | 0.5 | 0.5 | 3.8 | 4.2 | 3.8 | 5.8 |
| 959 | + | 80 | Ia | 0.25 | 2 | 4.6 | 5.8 | 3.5 | 5.1 |
| 970 | + | 728 | Ib | 0.25 | 1 | 4.9 | 5.9 | 3.5 | 4.7 |
| 1117 | + | 80 | Ib | 0.5 | 1 | 2.4 | 4.4 | 3.4 | 4.9 |
| 1512 | + | 30 | Ic | 0.25 | 1 | 5.4 | 5.4 | 4.4 | 5.9 |
| 1546 | + | 80 | Ic | 0.25 | 1 | 5 | 5.8 | 3.6 | 5.0 |
| 2629 | + | 80 | Ib | 0.25 | 1 | 4.9 | 6 | 3.8 | 6 |
| 4324 | + | 80 | Ib | 0.25 | 1 | 3.6 | 4.7 | 3.7 | 3.8 |
| 5014 | − | 80 | II | 0.5 | 1 | 4.2 | 5.7 | 2.7 | 4.2 |
| 5505 | + | 80 | Ib | 1 | 1 | 3.6 | 4.4 | 3 | 5.4 |
| 6036 | + | 80 | Ia | 0.5 | 1 | 5.1 | 6 | 3.8 | 5.8 |
| 6601 | + | 80 | Ib | 0.25 | 1 | 5 | 5.4 | 4 | 5.2 |
| 7059 | + | 80 | Ib | 0.25 | 1 | 4.9 | 5.0 | 3.9 | 6 |
| 9131 | + | 80 | Ib | 0.25 | 1 | 3.5 | 4.3 | 3.9 | 4.7 |
| 9833 | + | 80 | Ib | 0.5 | 1 | 2.7 | 4.8 | 3.3 | 5.5 |
| ATCC 29213 | − | ND | III | 0.25 | 1 | 5 | 6 | 3.5 | 6 |
| 7263 | + | ND | IV | 256 | 1 | 2 | 2 | 4.5 | 5.8 |
a
OXA, oxacillin; VAN, vancomycin; ND, not determined.