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Site and pathophysiology of glaucomatous optic neuropathy
| Where is the primary site of injury? |
| Intraocular retinal ganglion cell axon |
| Laminar retinal ganglion cell axon |
| Retinal ganglion cell body |
| What is the primary mechanism and subsequent sequence of injury? |
| Obstructed axoplasmic flow |
| Oxidative/free radical insult |
| Starvation/growth factor deprivation |
| Excitotoxicity |
| Nitric oxide (NO) toxicity |
| Apoptosis (retinal ganglion cell suicide/programmed cell death) |
