Table 1.

Cytotoxic effects of rilpivirine on human preadipocytes^a

Drug	Mean ± SEM percent cytotoxicity at a drug concn (μM) of:
	0.01	0.1	1	2	4	10
Rilpivirine	−0.2 ± 0.03	0.9 ± 0.08	−1.1 ± 0.12	0.1 ± 0.02	0.1 ± 0.01	5.1 ± 0.3*
Efavirenz	ND	ND	−0.1 ± 0.01	0.2 ± 0.01	0.1 ± 0.02	98 ± 7

^aPreadipocytes were treated with the indicated drugs for 5 days. Data are expressed as means ± SEMs of the percent cytotoxicity (LDH activity in the cell culture medium) relative to the 100% cytotoxicity control (LDH activity after total lysis of cells). The asterisk indicates a significantly different value (P < 0.05) from 0. ND, not determined.