Intercontinental spread and hospital transmission of MRSA ST239 isolates. Maximum likelihood phylogenetic tree based on differences (SNPs) in the core genomes of 63 ST239 isolates. The continent from which each isolate was obtained is indicated by the colour of the isolate name: blue, Asia; black, North America; green, South America; red, Europe; and yellow, Australasia. The Thai cluster, representing isolates from a single hospital, is displayed in greater resolution. Two of the isolates in this cluster were from Europe; however, one was recovered from a Thai patient. Even though the isolates are all the same by MLST, among the 63 isolates, variation is found at 4310 nucleotide positions and the sequence of each isolate is different. Reproduced from reference 14 with kind permission from the American Association for the Advancement of Science.