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Response of EMRSA-16 to subinhibitory and suprainhibitory concentrations of compounds 57 (a and b), 28 (c and d), 29 (e and f) and 36 (g and h). Compounds were added to mid-logarithmic-phase cultures (OD600 ∼ 0.1; 3 h), OD600 measured (a, c, e and g) and viable numbers determined (b, d, f and h): filled circles, no drug; open circles, 0.5× MIC; filled triangles, 1× MIC; open triangles, 2× MIC; and filled squares, 4× MIC. Error bars represent ±1 SD; n = 3.
