Table 3.

Comparison of microarray and qRT-PCR data following exposure of EMRSA-16 to PBD-biaryl conjugates 28 and 57 at concentrations of 0.5× MIC

Gene	Compound	Microarray	qRT-PCRa
grlA	57	1.03	0.75
	28	1.14	1.37
grlB	57	0.92	1.57
	28	1.05	1.54
gyrA	57	3.44*	4.20**
	28	1.10	1.11
gyrB	57	3.63	7.79**
	28	1.03	1.49
samB	57	17.25*	128.41**
	28	5.34*	28.28**
uvrA	57	2.95*	4.97**
	28	2.17*	2.91**
uvrB	57	3.55*	7.83**
	28	2.38*	3.95**
cap5L	57	0.28*	0.11**
	28	0.60	0.80
mnhD	57	0.35*	0.23**
	28	0.91	0.75

^amRNA expression levels were normalized to 16S rRNA.

*P < 0.05.

**P < 0.001.