Table 2. Percentage identity of the amino-acid sequences of selected metalloproteinases.
| Protein (No. of residues) | Sequence identity† (%) | R.m.s. deviation (Å)/No. of Cα atoms |
|---|---|---|
| hADAM-8 (201) | 100 | — |
| hADAM-33 (252) | 44 | 0.744/144 |
| Adamalysin II (197) | 38 | 0.695/157 |
| Atrolysin C (203) | 35 | 0.835/154 |
| hADAMTS-1 (210) | 27 | 0.806/118 |
| hADAMTS-4 (211) | 25 | 0.693/126 |
| hADAMTS-5 (210) | 25 | 0.780/140 |
| hADAM-17 (200) | 21 | 1.906/124 |
| hMMP-12 (182) | 10 | ND‡ |
| hMMP-13 (186) | 9 | ND‡ |
| hMMP-8 (184) | 4 | ND‡ |
†
Sequence alignment was performed using ClustalW (Thompson et al., 2002 ▶).
‡
No significant structural similarity was detected.