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. 2012 Jun 8;7(6):e37370. doi: 10.1371/journal.pone.0037370

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Komarov et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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In this simulation there are two cells. Each has two types of reactants of species type A, B. Internally there is a single reaction for each cell. Figure 4a shows the configuration at time when there is no physical overlap (therefore no interaction) between the cells. The size of the total reaction network is 2. Figure 4b shows overlap between the cells. This sets up diffusion (due to cell membrane paths that may open) of species between the two cells, thus increasing the size of the total reaction network to 6. This sets up a problem where there is a dynamic rearrangement of the total chemical network based on cell configuration.

Inline graphic — In this simulation there are two cells. Each has two types of reactants of species type A, B. Internally there is a single reaction for each cell. Figure 4a shows the configuration at time when there is no physical overlap (therefore no interaction) between the cells. The size of the total reaction network is 2. Figure 4b shows overlap between the cells. This sets up diffusion (due to cell membrane paths that may open) of species between the two cells, thus increasing the size of the total reaction network to 6. This sets up a problem where there is a dynamic rearrangement of the total chemical network based on cell configuration.