Skip to main content
. 2012 Jun 8;7(6):e38116. doi: 10.1371/journal.pone.0038116

Figure 3. Structural and functional assessment of the bilateral amygdala in our group of three Urbach-Wiethe Disease subjects.

Figure 3

Plotted are the cytoarchitectonic probability-maps of the amygdalae thresholded at 50%, structural lesion overlap, and functional activation during the emotion-matching task (contrast: Emotion>Shape matching, significant clusters p<.05, FDR-corrected for paired samples t-tests within ROI’s analysed separately for each hemisphere) on a template brain. The structural method indicates that the lesions of the three UWD subjects are located in the basolateral amygdala (BLA), while the functional method shows activation during emotion matching in the superficial amygdala (SFA) and central-medial amygdala (CMA), but not in the BLA.