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Cells treated with 500 µM METH for 1 h were assessed for production of ROS using DCFH-DA assay. A significant increase in ROS production is seen in cells knocked down for PDIA3, compared to PDIA3 expressors, both with and without METH treatment. Two-way ANOVA p<0.0001, Bonferroni post-tests. ***p<0.001. U – No treatment; M – METH treatment.
