Table 1.

Diagnostic Test Characteristics of TB case-ascertainment strategies using ICD9-CM data and two different sets of pharmacy criteria. A) ICD9-CM coded patient-provider encounters (010–018, V12.01, V01.1, and 647.3) and pharmacy data (two anti-tuberculosis medications (isoniazid, rifampin, pyrazinamide, ethambutol, rifabutin, amikacin and fluoroquinolones) filled on the same day). B) ICD9-CM coded patient-provider encounters and pharmacy data (isoniazid and rifampin filled on the same day, or any prescription for rifamate (isoniazid/rifampin combination) or pyrazinamide)

TABLE 1A. Diagnostic Test Characteristics of strategies based on ICD-9CMa and pharmacyb data for diagnosis of TB
TB Definition	N TB cases	Sensitivity % (95% CI)	Specificity % (95% CI)	PPV % (95% CI)	NPV % (95% CI)
ICD9-CM	449	60 (26.2–87.8)	97.6 (97.3–97.8)	1.3 (0.5–2.9)	99.9 (99.9–100)
Pharmacy	49	20 (2.5–55.6)	99.7 (99.7–99.8)	4.1 (0.5–14.3)	99.9 (99.9–100)
Both	8	20 (2.5–55.6)	99.9 (99.9–100)	25 (3.2–65.1)	99.9 (99.9–100)
TABLE 1B. Diagnostic Test Characteristics of strategies based on ICD9-CMa and pharmacyc data for diagnosis of TB
TB Definition	N TB cases	Sensitivity % (95% CI)	Specificity % (95% CI)	PPV % (95% CI)	NPV % (95% CI)
ICD9-CM	449	60 (26.2–87.8)	97.6 (97.3–97.8)	1.3 (0.5–2.9)	99.9 (99.9–100)
Pharmacy	12	20 (2.5–55.6)	99.9 (99.9–100)	16.7 (2.1–48.4)	100 (99.9–100)
Both	6	20 (2.5–55.6)	100 (99.9–100)	33.3 (4.3–77.7)	100 (99.9–100)