Table 1. Exonic histone modifications.

Summary of intragenic histone modifications associated with pre-mRNA splicing genome-wide and in specific model genes.

Histone modification	Genome wide association	Inclusion model	Exclusion model
H3K36me1	a[182]
H3K36me3	b[140, 142, 182] c [111]	Inclusion of variant exons of CD44 [172]	Exclusion of exon 18 of NCAM [151]. Exclusion of exon IIIb of FGFR [153].
H3K9me3		Inclusion of variant exons of CD44[81]
H3K27me1	a[182] b[140]
H3K27me2	b[140] d[143]
H3K27me3	b[140] a[182]		Exclusion of exon IIIc of FGFR [153]
H3K4me1	d[143]		Exclusion of exon IIIb of FGFR[153].
H3K4me3			Exclusion of exon IIIc of FGFR [153].
H3K20me1	d[142]
H3K79me1	b[140]
H3BK5me1	b[140] d[142]
H3K9ac			Exclusion of exon 18 of NCAM [151].

^aGenome wide association with alternative exon exclusion.

^bGenome wide association with alternative exon inclusion.

^cGenome wide reduction at alternative exons as compared to constitutive exons.

^dGenome wide data increased detection at exons relative to introns.