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. Author manuscript; available in PMC: 2013 Jul 1.
Published in final edited form as: Parasite Immunol. 2012 Jul;34(7):372–382. doi: 10.1111/j.1365-3024.2012.01367.x

Figure 5. CD36 regulates P. falciparum merozoite-induced pro-inflammatory cytokine production by DCs.

Figure 5

FL-DCs derived from WT and CD36−/− mice were plated into 96 well plates (1 × 105 cells per well) and stimulated with MZs (1 to 280 × 105 MZs/ml) to obtain the indicated ratios of DCs to MZs or polynucleosomes (0.5–2.5 μg/ml DNA content) in 200 μl of culture medium. TNF-α and IL-12 released into the culture medium were analyzed by ELISA. FL-DCs similarly stimulated with LPS (100 ng/ml) or CpG (2 μg/ml) were analyzed as controls. Data are representative of three independent experiments. Mean values ± SD are plotted. *, p <0.05; **, p <0.01.