(A) CRF is localized in numerous regions of the cochlea. The highest immunofluorescence intensities are located in the inner hair cell region (IHC), the spiral ganglion cells (SGC) and the associated afferent fibers, and in the lateral support cells along the basilar membrane (arrowheads) extending up the lateral wall to the spiral prominence (SP). Also, the stria vascularis (SV) is moderately labeled for CRF. (B) In the organ of Corti, inner hair cells (IHC) and outer hair cells (OHCs) are immunolabeled for CRF. The Deiter’s cells are also immunopositive, but are less intensely labeled. (reprinted from (Graham et al., 2010) with permission)