Table 5.

Multivariate analysis of prognostic factors using Cox's proportional hazard model

Covariate	P-value*	Hazard ratio (95% CI)
Biliary drainage (BD vs. non-BD)	0.2875	0.717 (0.389–1.323)
PS (1 vs. 0)	0.1620	1.532 (0.843–2.785)
Primary tumour site (gallbladder vs. non-gallbladder)	0.0454	1.722 (1.011–2.934)
Presence of primary tumour (present vs. absent)	0.0036	2.789 (1.398–5.564)
Extent of disease (metastatic vs. locally advanced)	0.4333	1.391 (0.609–3.176)
Treatment arm (GC arm vs. G arm)	0.2093	0.724 (0.437–1.199)

^*Chi-square test.

BD, biliary drainage; CI, confidence interval; G arm, emcitabine monotherapy; GC arm, combination therapy with gemcitabine and cisplatin; PS, performance status.