Table 4.
Spearman correlation coefficients showing the correlations between measures of disease activity (BASDAI score) and MRI activity score and between inflammation (CRP level) and MRI activity score for patients in the combined golimumab group
| ASspiMRI-a score | |||
|---|---|---|---|
| Baseline | Change from baseline to week 14 | Change from baseline to week 104 | |
| CRP | |||
| Baseline | 0.38† | −0.44‡ | −0.40‡ |
| Change from baseline to week 14 | 0.45‡ | 0.39† | |
| Change from baseline to week 104 | 0.38† | ||
| ASDAS | |||
| Baseline | 0.23 | −0.30* | −0.33† |
| Change from baseline to week 14 | 0.35† | 0.19 | |
| Change from baseline to week 104 | 0.22 | ||
| BASDAI | |||
| Baseline | 0.06 | −0.06 | −0.16 |
| Change from baseline to week 14 | 0.26* | 0.16 | |
| Change from baseline to week 104 | 0.11 | ||
| BASFI | |||
| Baseline | 0.08 | 0.01 | −0.21 |
| Change from baseline to week 14 | 0.19 | 0.10 | |
| Change from baseline to week 104 | 0.05 | ||
| Total back pain | |||
| Baseline | 0.06 | −0.16 | −0.16 |
| Change from baseline to week 14 | 0.15 | −0.01 | |
| Change from baseline to week 104 | 0.02 | ||
| Morning stiffness | |||
| Baseline | −0.03 | −0.07 | −0.09 |
| Change from baseline to week 14 | −0.14 | 0.02 | |
| Change from baseline to week 104 | 0.06 | ||
*
p<0.05.
†
p<0.01.
‡
p<0.001.
ASDAS, ankylosing spondylitis disease activity score; ASspiMRI-a, ankylosing spondylitis spinal magnetic resonance imaging activity; BASDAI, Bath ankylosing spondylitis disease activity index; BASFI, Bath ankylosing spondylitis functional index; CRP, C-reactive protein.