Skip to main content
. 2012 May 2;32(18):6312–6322. doi: 10.1523/JNEUROSCI.6517-11.2012

Figure 4.

Figure 4.

Suppression of the overgrowth phenotype of octß1r by decreasing cAMP. A, B, Quantification of natural synaptopods per 100 μm of type II arbor (A) and type II boutons at muscle 12 (B) in octß1r mutants, rut mutants, animals overexpressing Dnc in type II and combinations of these genetic manipulations, showing that rut and overexpressing Dnc fully suppress the synaptic overgrowth phenotype of octß1r, suggesting that Rut and Dnc are downstream components of the Octß1R signaling pathway [N (left to right) = 175, 21, 24, 13, 14, 13 NMJs in A; N (left to right) = 22, 15, 18, 18, 12, 12 NMJs in B]. C, D, Quantification of natural synaptopods per 100 μm of type II arbor (C) and type II boutons at muscle 12 (D) in octß2r mutants, octß1r mutants, and octß1r, octß2r double mutants, showing that Octß1R and Octß2R function partially independently [N (left to right) = 175, 13, 21, 12 NMJs in C; N (left to right) = 22, 17, 15, 16 NMJs in D]. Error bars indicate SEM. ***p < = 0.0001; **p < = 0.001; *p < 0.05.