Table 1.

Summary of Studies

Study	Study ID	# of Subjects	Treatment		Placebo		Female		Age mean(sd)	Dosing (mg/day)
			n	%	n	%	n	%
Lilly - Adult	C031	69	37	53.6	32	46.4	46	66.7	38.7 (9.1)	20
	HCAC	110	55	50.0	55	50.0	77	70.0	40.2 (12.5)	20–80
	HCAF	475	244	51.4	231	48.6	311	65.5	40.3 (12.3)	40–80
	HCCH	90	45	50.0	45	50.0	45	50.0	41.8 (12.0)	40–80
	HCCP	733	626	85.4	107	14.6	421	57.4	39.4 (11.4)	20, 40, 60
	HCDD	363	285	78.5	78	21.5	221	60.9	38.9 (11.1)	5, 20, 40
	HCFP	89	46	51.7	43	48.3	63	70.8	40.4 (10.4)	20
	HLAB	166	93	56.0	73	44.0	86	51.8	43.2 (9.6)	20
	HMAQA	103	33	32.0	70	68.0	67	65.0	40.8 (12.3)	20
	HMAQB	112	37	33.0	75	67.0	73	65.2	40.8 (12.1)	20
	HZAA	128	63	49.2	65	50.8	76	59.4	40.0 (10.1)	10–20
	LUAB	197	63	32.0	134	68.0	128	65.0	40.0 (11.2)	20
Lilly - Geriatric	HCCQ	90	59	65.6	31	34.4	64	71.1	73.9 (6.1)	20, 40
	HCFF	670	335	50.0	335	50.0	366	54.6	67.7 (5.7)	20
	HCIR	121	57	47.1	64	52.9	88	72.7	83.7 (5.1)	10–30
	HC55	79	39	49.4	40	50.6	59	74.7	80.7 (6.2)	20
Lilly - Child	HCJE	219	109	49.8	110	50.2	108	49.3	12.7 (2.6)	10–20
	LYAQ	172	127	73.8	45	26.2	48	27.9	11.3 (2.6)	10–40
	X065	96	48	50.0	48	50.0	44	45.8	12.8 (2.7)	20
TADS		221	109	49.3	112	50.7	118	53.4	14.6 (1.6)	10, 20, 40
Wyeth - ER	014	202	100	49.5	102	50.5	121	59.9	40.3 (11.4)	37.5–225
	105	198	102	51.5	96	48.5	100	50.5	71.0 (5.1)	37.5–225
	016	189	94	49.7	95	50.3	107	56.6	40.9 (12.9)	37.5–375
	208	197	97	49.2	100	50.8	119	60.4	39.8 (10.5)	75–150
	209	197	95	48.2	102	51.8	121	61.4	40.7 (11.4)	75–225
	211	198	100	50.5	98	49.5	136	68.7	39.7 (11.7)	75–225
	360	246	127	51.6	119	48.4	147	59.8	41.4 (11.5)	75–225
	367	248	165	66.5	83	33.5	168	67.7	44.6 (11.7)	75, 150
	402	395	295	74.7	100	25.3	239	60.5	38.8 (13.1)	37.5–300
	414	391	292	74.7	99	25.3	260	66.5	42.2 (13.5)	37.5–300
Wyeth - IR	203	358	266	74.3	92	25.7	139	38.8	43.0 (10.7)	75, 150–225, 300–375
	206	93	46	49.5	47	50.5	79	84.9	65.2 (13.3)	150–375
	208	196	96	49.0	100	51.0	124	63.3	41.1 (11.0)	75–150
	300	108	58	53.7	50	46.3	33	30.6	43.6 (12.0)	150–375
	301	151	73	48.3	78	51.7	104	68.9	41.7 (12.7)	75–225
	302	148	72	48.6	76	51.4	96	64.9	41.7 (11.6)	75–200
	303	159	79	49.7	80	50.3	109	68.6	38.9 (9.8)	75–225
	313	312	234	75.0	78	25.0	210	67.3	38.5 (10.3)	25, 50–75, 150–200
	342	384	286	74.5	98	25.5	245	63.8	41.8 (11.7)	75, 150, 200
	343	205	136	66.3	69	33.7	153	74.6	38.7 (10.5)	150, 225
	372	307	156	50.8	151	49.2	190	61.9	39.9 (10.0)	missing