Figure 7.
Line graphs depict brain interstitial levels of 2′,3′-cAMP, 2′-AMP and 3′-AMP in CNPase +/+ mice (Wild-Type) and CNPase −/− mice (KO) either subjected to controlled cortical impact (CCI) or sham impact (SHAM): (A) 2′,3′-cAMP in CNPase +/+; (B) 2′,3′-cAMP in CNPase −/−; (C) 2′-AMP in CNPase +/+; (D) 2′-AMP in CNPase −/−; (E) 3′-AMP in CNPase +/+; (F) 3′-AMP in CNPase −/−. “a” indicates significantly different from baseline in the corresponding group. “b” indicates significantly different from SHAM at the corresponding period. “c” indicates significantly different at the corresponding period from CNPase +/+ mice subjected to CCI. Values represent mean ± SEM.