. Author manuscript; available in PMC: 2012 Oct 1.

Published in final edited form as: Gastrointest Endosc. 2011 Oct;74(4):885–896. doi: 10.1016/j.gie.2011.06.023

TABLE 4.

Incidence rates for specific adverse events related to colonoscopy stratified by longest patient follow-up time

	Day of procedure (incidence per 1000 colonoscopies)	≤7 d (incidence per 1000 colonoscopies)	≤30 d (incidence per 1000 colonoscopies)
Patients ≥65 y^*
Perforation^†	^‡	1.1 (1.0–1.3)^12,20,23,29	0.6 (0.4–0.9)^16,20,26,27
GI bleeding	^§	0 (0.1–23.6)^20,23	6.3 (5.7–7.1)^16,20,26
CV/pulm	^\|\|	51.3 (26.8–87.9)^20,23	19.0 (17.9–20.2)^16,20,26
Mortality	^¶	0 (0.1–23.6)^20,23	1.0 (0.7–1.3)^16,20,26
Patients ≥80 y
Perforation^#^**	1.5 (0.5–3.6)^{11,17–19,21,22,24,25,28}	1.5 (1.2–1.9)^12,29	0 (0.06–12.6)^15,30
GI bleeding^#	2.5 (1.1–4.8)^{11,17–19,21,22,24,25,28}	^††	^§§
CV/pulm^#	12.4 (9.0–16.6)^{11,13,14,17–19,21,22,24,25,28}	^††	34.2 (30.9–37.8)^15,16
Mortality^#^**	0.6 (0.07–2.1)^{11,13,17–19,21,22,24,25,28}	^††	0 (0.06–12.6)^15,30

Values shown are confidence intervals.

Note: All incidence rates for adverse events are calculated based on the entire time period for which patients were followed in the study. However, some studies may have identified specific adverse events earlier than their reported patient follow-up. These studies are identified in the footnotes that follow.

CV/pulm, Cardiovascular/pulmonary.

DiPrima et al²⁰ study divided patients into 2 groups for follow up.

^†

Nelson et al²⁷ study also reported adverse event data for ≤7 days after colonoscopy.

^‡

Three studies with longer patient follow-up times had data recorded on the day of the procedure with respect to perforation (1.5; 95% CI, 0.2–5.3).^20,23,26

^§

Three studies with longer patient follow-up times had data recorded on the day of the procedure with respect to GI bleeding (0; 95% CI, 0.02–4.1).^20,23,26

^||

Three studies with longer patient follow-up times had data recorded on the day of the procedure with respect to CV/pulmonary complications (10.2; 95% CI, 5.6–17.1).^20,23,26

^¶

Three studies with longer patient follow-up times had data recorded on the day of the procedure with respect to mortality (0; 95% CI, 0.02–4.1).^20,23,26

Sardinha et al¹⁵ study also reported adverse event data on the day of colonoscopy.

^**

Ko et al³⁰ study also reported adverse event data for ≤7 days after colonoscopy.

^††

No data available.

^§§

Data only available from 1 study.