Table 7.
Association of physical activity with non-advanced adenomas and advanced adenomas
| Parameter | Non-advanced adenoma vs. no adenoma | Advanced adenoma vs. no adenoma | ||||
|---|---|---|---|---|---|---|
| Non-advanced adenoma/no adenoma |
Crude OR (95% CI) |
Adjusteda OR (95% CI) |
Advanced adenoma/no adenoma |
Crude OR (95% CI) |
Adjusteda OR (95% CI) |
|
| Total PAS-M (kcal/kg/week) | ||||||
| 1st tertile (<120) | 57/63 | 1.0 (reference) | 1.0 (reference) | 11/63 | 1.0 (reference) | 1.0 (reference) |
| 2nd tertile (120–200) | 36/82 | 0.49 (0.29, 0.83) | 0.51 (0.27, 0.96) | 12/82 | 0.84 (0.35, 2.0) | 0.83 (0.29, 2.3) |
| 3rd tertile (≥200) | 34/89 | 0.42 (0.25, 0.72) | 0.47 (0.25, 0.89) | 8/89 | 0.52 (0.20, 1.4) | 0.41 (0.13, 1.4) |
| P-value for trend | 0.001 | 0.02 | 0.18 | 0.16 | ||
| Moderate PAS-M (kcal/kg/week) | ||||||
| 1st tertile (<22) | 37/73 | 1.0 (reference) | 1.0 (reference) | 17/73 | 1.0 (reference) | 1.0 (reference) |
| 2nd tertile (22–67) | 52/76 | 1.4 (0.80, 2.3) | 1.7 (0.89, 3.3) | 8/76 | 0.45 (0.18, 1.1) | 0.32 (0.11, 0.95) |
| 3rd tertile (≥67) | 38/84 | 0.89 (0.52, 1.6) | 1.2 (0.58, 2.3) | 6/84 | 0.31 (0.12, 0.82) | 0.17 (0.044, 0.64) |
| P-value for trend | 0.66 | 0.81 | 0.01 | 0.004 | ||
| TES-M (kcal/day) | ||||||
| 1st tertile (<2,027) | 53/67 | 1.0 (reference) | 1.0 (reference) | 12/67 | 1.0 (reference) | 1.0 (reference) |
| 2nd tertile (2,027–2,643) | 38/80 | 0.60 (0.35, 1.0) | 0.68 (0.36, 1.3) | 11/80 | 0.77 (0.32, 1.9) | 0.76 (0.27, 2.1) |
| 3rd tertile (≥2,643) | 36/87 | 0.52 (0.31, 0.89) | 0.65 (0.34, 1.2) | 8/87 | 0.51 (0.20, 1.3) | 0.33 (0.095, 1.2) |
| P-value for trend | 0.02 | 0.18 | 0.17 | 0.09 | ||
| PAS-P (kcal/kg/week) | ||||||
| 1st tertile (<5.6) | 38/82 | 1.0 (reference) | 1.0 (reference) | 8/82 | 1.0 (reference) | 1.0 (reference) |
| 2nd tertile (5.6–13.8) | 49/71 | 1.5 (0.88, 2.5) | 2.4 (1.2, 4.5) | 15/71 | 2.2 (0.87, 5.4) | 3.6 (1.2, 11) |
| 3rd tertile (≥13.8) | 41/82 | 1.1 (0.63, 1.8) | 1.5 (0.75, 2.9) | 8/82 | 1.0 (0.36, 2.8) | 1.2 (0.32, 4.8) |
| P-value for trend | 0.79 | 0.31 | 1.0 | 0.76 | ||
OR odds ratio, CI confidence interval, PAS-M Morgenstern physical activity score, TES-M Morgenstern total energy score, PAS-P Paffenbarger physical activity score
a
Adjusted for waist circumference, age, tobacco use, first degree family history of colorectal cancer, and indication of colonoscopy