Table 2.

FDA approved indications for use of proton pump inhibitors [8–14].

(1) Healing of erosive esophagitis

(2) Maintenance of healing of erosive esophagitis

(3) Symptomatic gastroesophageal reflux disease

(4) Helicobacter pylori eradication in combination with antibiotics

(5) Short-term treatment of active gastric ulcer

(6) Short-term treatment of active duodenal ulcer

(7) Maintenance of healed duodenal ulcer

(8) Healing of NSAID-Associated gastric ulcer

(9) Risk reduction of NSAID-associated gastric Ulcer

(10) Risk reduction of upper gastrointestinal bleeding in critically Ill patients

(11) Pathological hypersecretory conditions including Zollinger-Ellison syndrome

Abbreviations: FDA, Food and Drug Administration; NSAID, non-steroidal anti-inflammatory drugs.