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. Author manuscript; available in PMC: 2013 Jul 1.
Published in final edited form as: Epidemiology. 2012 Jul;23(4):616–622. doi: 10.1097/EDE.0b013e31825583a0

TABLE 2.

Association of the 32 Prostate Cancer SNPs in 26 Chromosomal Regions with the Risk for Prostate Cancer

SNP Region Reported
Gene(s)		 Minor
Allele		 Minor
Allele
Frequency
(%)		 P-values Odds Ratio
Family-
history-
based		 Disease-
based		 Family-
history-
based		 Disease-
based
rs721048 2p15 EHBP1 A 19 0.644 NA 0.76 NA
rs1465618 2p21 THADA A 21 0.350 0.871 1.06 1.01
rs12621278 2q31.1 ITGA6 G 6 0.023 0.466 0.74 0.93
rs17181170 3p12.1 NR A 49 0.070 0.015 0.90 0.89
rs2660753 3p12.1 Intergenic T 12 0.114 0.217 1.14 1.09
rs10934853a 3q21.3 Intergenic A 28 0.142 0.004 1.09 1.16
rs12500426 4q22.3 PDLIM5 A 46 0.983 0.131 1.00 1.07
rs7679673 4q24 TET2 A 41 0.510 0.003 1.05 0.86
rs10498792 6p12.2 PKHD1 C 11 0.908 0.860 0.99 0.99
rs9364554 6q25.3 SLC22A3 T 29 0.610 0.396 0.97 1.04
rs10486567 7p15.2 JAZF1 A 23 0.686 0.007 1.03 0.86
rs6465657 7q21.3 JAZF1 C 46 0.526 0.257 0.97 1.05
rs1512268 8p21.2 NKX3.1 A 43 0.004 0.158 1.18 1.07
rs1016343 8q24.21 Intergenic T 21 0.205 0.005 1.09 1.17
rs4242382 8q24.21 Intergenic A 11 7.4E-05 9.1E-07 1.38 1.40
rs6983267a 8q24.21 Intergenic T 49 0.159 7.2E-06 0.92 0.81
rs620861a 8q24 - T 37 0.014 0.173 0.87 0.94
rs1571801 9q33.2 - A 26 0.798 0.027 1.02 1.12
rs10993994a 10q11.23 MSMB T 39 0.156 0.013 1.08 1.12
rs3123078 10q11.23 NR C 44 0.529 0.023 1.04 1.11
rs4962416 10q26.13 CTBP2 C 29 0.711 4.3E-05 1.02 1.23
rs7127900 11p15.5 IGF2, IGF2AS, INS, TH A 19 0.381 0.075 1.06 1.11
rs10896449a 11q13.2 Intergenic A 49 0.061 0.001 0.90 0.85
rs11228565a 11q13.2 Intergenic A 19 0.892 NA 1.07 NA
rs7931342a 11q13.2 Intergenic T 49 0.058 0.001 0.90 0.86
rs4054823 17p12 - C 45 0.847 0.120 1.01 0.93
rs4430796 17q12 Intergenic G 47 0.253 0.268 0.94 0.95
rs1859962a 17q24.3 NR G 49 0.002 0.001 1.19 1.17
rs2735839 19q13.33 KLK3 A 15 0.271 0.049 1.09 0.88
rs9623117 22q13.1 TNRC6B C 23 0.509 0.048 0.96 1.12
rs5759167 22q13.2 NR T 50 0.023 0.001 0.88 0.86
rs5945572a Xp11.22 NUDT10, NUDT11, LOC340602, GSPT2, MAGED1 A 37 0.722 0.001 0.98 1.12
Gray cells have p-values less than 0.05
a

SNPs discovered by the Cancer Genetic Markers of Susceptibility Prostate Cancer GWA study