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. 2011 Sep 21;31(38):13420–13430. doi: 10.1523/JNEUROSCI.2075-11.2011

Figure 1.

Figure 1.

Normal gross brain morphology of MAGL−/− mice. A, Genotyping of MAGL+/+, MAGL+/−, and MAGL−/− mice was performed by PCR using ear DNA. The 430 bp band corresponds to the wild-type allele and the 220 bp band corresponds to the gene-trapped allele. B, C, Nissl staining of parasagittal sections of the brains of MAGL+/+ (B) and MAGL−/− mice (C) show similar gross brain morphology. Scale bars, 1 mm. N = 3 mice each phenotype. D, Immunohistochemical analysis of the hippocampus of MAGL+/+ and MAGL−/− mice using antibody against GAP-43, a marker of axonal growth and presynaptic terminals. No detectable difference of GAP-43 staining or hippocampal cytoarchitecture was found between MAGL+/+ and MAGL−/− mice. Scale bars, 0.5 mm. N = 3 mice each phenotype.