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. 2011 Sep 21;31(38):13420–13430. doi: 10.1523/JNEUROSCI.2075-11.2011

Figure 3.

Figure 3.

Genetic deletion of MAGL selectively facilitates TBS-induced LTP in hippocampal slices but had no significant effects on either HFS-induced LTP or LFS-induced LTD. A, Five-burst TBS protocol induced LTP in MAGL−/− mice (n = 9; N = 5 mice) but not in MAGL+/+ mice (n = 8; N = 4; p < 0.05). B, Fifteen-burst TBS protocol induced LTP with greater magnitude in MAGL−/− mice (n = 9; N = 4) than that in MAGL+/+ mice (n = 7; N = 3; p < 0.01). C, HFS protocol induced similar LTP in MAGL−/− mice (n = 9; N = 6) and MAGL+/+ mice (n = 8; N = 5; p > 0.05). D, There was no significant difference of LFS-induced LTD between MAGL+/+ mice (n = 8; N = 4) and MAGL−/− mice (n = 7; N = 4; p > 0.05).