Table 1. Summary of metastatic disease burden in KPC mice.
Treatment | % mice with mets |
# macroscopic mets / mouse (mean+/−S.E.M.) |
# mets / mouse (mean+/−S.E.M.) |
% mice with liver mets |
% mice with lung mets |
% mice with diaphragm mets |
% lymph node involvement |
% mice with malignant ascites |
---|---|---|---|---|---|---|---|---|
Gem+Placebo | 93 | 1.7 +/− 0.35 | 2.4 +/− 0.35 | 73 | 40 | 40 | 73 | 47 |
Gem+PEGPH20 | 43 | 0.86 +/− 0.4 | 1.1 +/− 0.4 | 43 | 21 | 21 | 36 | 21 |