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. Author manuscript; available in PMC: 2013 May 25.
Published in final edited form as: Circ Res. 2012 Apr 17;110(11):1474–1483. doi: 10.1161/CIRCRESAHA.112.268094

Figure 4. Reduced cardiac remodeling associated with heart failure following TAC in S2814A mice.

Figure 4

A. Representative photographs of sections at the midsaggital level of hearts stained with Masson’s Trichrome (scale bar = 1 mm). B. Quantification of cardiac fibrosis at 16 weeks after sham or TAC surgery. C. Post-mortem measurements of lung weight to tibia length (LuW/TL) ratios 16 weeks after TAC. D, E. mRNA transcript levels of cardiac stress genes ANF (D) and BNP (E) by real-time PCR. Numbers in bar indicate number of animals. * P<0.05, ** P<0.01 versus corresponding sham group; # P<0.05, ## P<0.01 versus WT TAC.