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. Author manuscript; available in PMC: 2013 May 25.
Published in final edited form as: Circ Res. 2012 Apr 17;110(11):1474–1483. doi: 10.1161/CIRCRESAHA.112.268094

Figure 6. Inhibition of CaMKII phosphorylation of RyR2 attenuates SR Ca2+ Leak after TAC.

Figure 6

A. Representative images of spontaneous Ca2+ release (SCR) events in ventricular myocytes after 1Hz pacing. B. Incidence of SCR events in isolated myocytes from sham-operated and mice 16 weeks after TAC, before and after pre-treatment with KN93, respectively. C. Quantification of SCR events per cell before and after pre-treatment with KN93. N=30–75 cells from 3–6 mice per group. ** P<0.01 versus corresponding sham, ## P<0.01 versus WT TAC.