Table 4.
Gram-negative | Gram-positive | Yeast | |||
---|---|---|---|---|---|
Compound | S. typhimurium | E. coli | B. cereus | S. aureus | S. cerevisiae |
1a [Au2(mes)2(μ-dppe)] | Ins[b] | Ins[b] | 10 | 10 | Ins[b] |
2a [Au2Ag(μ-mes)2(μ-dppe)]ClO4 | 10 | 10 | 1 | 10 | >100[c] |
3a [Au2Ag(μ-mes)2(μ-dppe)]SO3CF3 | 10 | 10 | 10 | 10 | >100[c] |
4a [Au2Cu(μ-mes)2(μ-dppe)]PF6 | Ins[b] | Ins[b] | 10 | 10 | Ins[b] |
5a [Au2Cl2(μ-dppe)] | >100[c] | >100[c] | >100[c] | >100[c] | >100[c] |
AgOClO3 | 100 | 100 | 10 | 100 | 100 |
AgOSO2CF3 | 100 | 100 | 10 | 100 | 100 |
1b [{Au(mes)}2(μ-dppy)] | >100[c] | >100[c] | >100[c] | >100[c] | >100[c] |
2b [Au2Ag(μ-mes)2(μ-dppy)]ClO4 | 100 | 100 | 100 | 100 | 100 |
3b [Au2Ag(μ-mes)2(μ-dppy)]SO3CF3 | 100 | 100 | 100 | 100 | 100 |
4b [Au2Cu(μ-mes)2(μ-dppy)]PF6 | >100[c] | >100[c] | 100 | 100 | >100[c] |
5b [{AuCl}2(μ-dppy)] | 100 | 100 | 100 | 100 | >100[c] |
Compounds were dissolved in DMSO.
Ins - The compound was insoluble in aqueous solution above 10 ug/ml.
Concentrations greater than 100 ug/ml were not tested because the compounds would not have been soluble.