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. 2012 Jun;22(6):1163–1172. doi: 10.1101/gr.130435.111

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© 2012, Published by Cold Spring Harbor Laboratory Press

This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first six months after the full-issue publication date (see http://genome.cshlp.org/site/misc/terms.xhtml). After six months, it is available under a Creative Commons License (Attribution-NonCommercial 3.0 Unported License), as described at http://creativecommons.org/licenses/by-nc/3.0/.

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Figure 3. — Overview of COOL clusters with known and predicted functions. Analyses of miR-155 (A), miR-1 (B), miR-130a (C), miR-519d (D), miR-190 (E), and miR-340 (F). The graphs represent the COOL heat-maps of putative targets generated according to their reciprocal expression relationships. (Red and yellow boxes) Clusters with an R² value higher or lower than the set threshold, respectively. (PTs) Predicted targets. Some of the functional categories enriched in the significant miRNA clusters are indicated.