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. Author manuscript; available in PMC: 2012 Jun 11.
Published in final edited form as: Melanoma Res. 2009 Oct;19(5):283–293. doi: 10.1097/CMR.0b013e32832b272d

Table 1. Cytotoxicity of KP46, dacarbazine, and cisplatin in 96-h cultures of two human melanoma cell lines after exposure for 1 h or continuous exposure in the MTT assay.

IC50 (μmol/l)
Compound 518A2
(1 h)		 518A2
(96 h)		 SK-MEL-28
(1 h)		 SK-MEL-28
(96 h)
KP46 9.4 ± 0.6 0.85 ± 0.20 15 ±2 2.5± 0.2
Dacarbazine 121 ± 18 2.5± 0.7 > 400 50± 23
Cisplatin 16 ± 4 0.79 ± 0.36 56 ±24 2.2± 0.1

IC50, 50% inhibitory concentration; KP46, tris(8-quinolinolato)gallium(III); MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide.