Table 1. Selected differentially expressed genes from the oligo microarray (rapamycin-exposed SSCs vs controls).
| Category | Fold Δ | p value | ||
|---|---|---|---|---|
| UP | DOWN | |||
| SSC self-renewal | ||||
| Gfra1 | 3.13411 | 4.35E-10 | ||
| Ret | 2.71904 | 4.69E-06 | ||
| Lin28b | 5.77946 | 0.00615 | ||
| Nanos 2 | 3.00648 | 0.00007 | ||
| Foxo1 | 2.3856 | 8.50E-08 | ||
| Signal transduction | ||||
| Wnt3a | 8.76346 | 1.98E-07 | ||
| Wnt2 | 3.28504 | 4.55E-10 | ||
| Stat4 | 7.53744 | 8.22E-18 | ||
| Tgfbr1 | 2.52916 | 3.41E-08 | ||
| Tgfbr2 | 2.41742 | 6.11E-08 | ||
| Tgfbr3 | 2.98383 | 8.50E-06 | ||
| Oxidative stress response | ||||
| Sod1 | 2.01295 | 8.69E-06 | ||
| Gsr | 2.74239 | 2.40E-09 | ||
| Alad | 5.23738 | 1.91E-15 | ||
| Gstm6 | 6.59408 | 5.00E-17 | ||
| Gstm7 | 7.34355 | 1.15E-17 | ||
| Brca1 | 2.91830 | 0.00183 | ||
| Nfe2l1 | 2.21224 | 5.94E-07 | ||
| Glrx2 | 2.75994 | 0.00039 | ||
| Other | ||||
| Erbb2 | 2.06434 | 1.49E-10 | ||
| Rb1 | 2.35478 | 3.73E-14 | ||
| Tnf | 2.67337 | 3.57E-18 | ||
| Gsc | 5.13706 | 1.74E-13 | ||
| Meox2 | 7.68215 | 3.37E-06 | ||