In OE33 Notch1, 3 and 4 mRNA levels are decreased by DCA in a concentration dependent manner. OE33 cells were exposed to DCA concentration (0–300 μM) for 8 h. RNA was extracted, reverse transcribed to cDNA and subjected to real-time PCR, n = 3: for Notch1: *P < .0001–P < .05 for all DCAs vs control and 200 vs 300 μM DCA. For Notch3: αP < .001–P < .01 for DCA vs control and vs each of DCA concentration. For Notch4: βP < .05 for 200 and 300 μM DCA vs control. C (0), 100, 200, 300 are DCA concentrations in μM.