Table 4: Genotype and allele frequencies in patients and healthy people.
SNP | Control | Patient | P-value | |||
N | % | N | % | |||
TNF-238 | Genotype | NSa | ||||
G/G | 98 | 95.1 | 84 | 90.3 | ||
G/A | 5 | 4.9 | 9 | 9.7 | ||
A/A | 0 | - | 0 | - | ||
Allele frequency | NS | |||||
G | 201 | 97.6 | 177 | 95.2 | ||
A | 5 | 2.4 | 9 | 4.8 | ||
TNF-244 | Genotype | NS | ||||
G/G | 103 | 100 | 93 | 100 | ||
G/A | 0 | - | 0 | - | ||
A/A | 0 | - | 0 | - | ||
Allele frequency | NS | |||||
G | 206 | 100 | 186 | 100 | ||
A | - | 0 | - | 0 | ||
TNF-308 | Genotype | NS | ||||
G/G | 87 | 84.5 | 84 | 90.3 | ||
G/A | 16 | 15.5 | 9 | 9.7 | ||
A/A | 0 | - | 0 | - | ||
Allele frequency | NS | |||||
G | 190 | 92.2 | 177 | 95.2 | ||
A | 16 | 7.8 | 9 | 4.8 | ||
TNF-857 | Genotype | 0.001 | ||||
C/C | 83 | 80.6 | 51 | 54.8 | ||
C/T | 18 | 17.5 | 42 | 45.2 | ||
T/T | 2 | 1.9 | 0 | - | ||
Allele frequency | 0.002b | |||||
C | 184 | 89.3 | 144 | 77.4 | ||
T | 22 | 10.7 | 42 | 22.6 | ||
TNF-863 | Genotype | NS | ||||
C/C | 74 | 71.8 | 69 | 74.2 | ||
C/A | 29 | 28.2 | 21 | 22.6 | ||
A/A | 0 | - | 3 | 3.2 | ||
Allele frequency | NS | |||||
C | 177 | 85.9 | 159 | 85.5 | ||
A | 29 | 14.1 | 27 | 14.5 |
a NS: Nonsignificant
b odds: 2.4, C.I 95% (1.3-4.4)