Table 4.

Parameters of steady-state slow inactivation in Na_V1.2 and Na_V1.5 at pH 7.4 and 6.0.

	NaV1.2	NaV1.5
SS_SImax,% (pH 7.4)	91.0 ± 1.1	64.0 ± 4.6
SS_SImax,% (pH 6.0)	98.0 ± 2.5	58.0 ± 3.5
z, Apparent valence (pH 7.4)	3.1 ± 0.6	1.9 ± 0.12
z, Apparent valence (pH 6.0)	3.7 ± 0.5	1.4 ± 0.1(2)
V1/2, mV (pH 7.4)	−52.5 ± 2.8	−71.4 ± 3.2
V1/2, mV (pH 6.0)	61.1 ± 3.7(1)	−57.4 ± 3.1(3)

⁽¹⁾p < 0.05 vs. V_1/2 at pH = 7.4 in Na_V1.2.

⁽²⁾p < 0.05 vs. apparent valence (z) at pH = 7.4 in Na_V1.5.

⁽³⁾p < 0.05 vs. V_1/2 at pH = 7.4 in Na_V1.5; n = 6.