. 2012 Jun;86(11):6084–6096. doi: 10.1128/JVI.06449-11

Table 1.

Mutations accompanying the generation of CHIKV vaccine strain 181/25 (AKA TSI-GSD-218) from its parent strain AF15561

Gene	Nucleotide position	Amino acid position	Amino acid substitution
nsP1	978	301	Thr→Ile
nsP2	3706^a
nsP4	7259^a
E3	8463^a
E2	8576	12	Thr→Ile
	8760^a
	8785	82	Gly→Arg
6K	9935	42	Cys→Phe
E1	10446^a
	11204	404	Ala→Val

Synonymous mutations.