Fig 6.

Effect of single PML isoforms on EBV reactivation and lytic infection. AGS-EBVshPML (shPML) cells were infected with lentivirus expressing individual PML isoforms I to VI. (A) The cells were fixed and stained 72 h postinfection for PML (green) and BZLF1 (red). (B) AGS-EBVshPML cells (−), parental AGS-EBV cells (+) and the single PML isoform cells (I to VI) were scored for whether or not they expressed BZLF1, and the percentages of BZLF1-positive cells were determined. For the single PML isoform samples, only the PML-positive cells were scored. Average values with standard deviations from three independent experiments are shown.